Company Description
Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary blood tests, vast data sets and advanced analytics. The Guardant Health Oncology Platform is designed to leverage our capabilities in technology, clinical development, regulatory and reimbursement to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs. In pursuit of our goal to manage cancer across all stages of the disease, Guardant Health has launched two liquid biopsy-based tests, Guardant360 and GuardantOMNI, for advanced stage cancer patients, and is developing programs for recurrence and early detection, called Project LUNAR. Since its launch in 2014, Guardant360 has been used by more than 5,000 oncologists, over 40 biopharmaceutical companies and all 27 of the National Comprehensive Cancer Network centers.
Job Description
Job Description
To enable Guardant Health to lead the disruption of cancer diagnostics through non-invasive cancer screening, the Technology Development Team is seeking a highly motivated Senior/Staff Research Associate to help develop novel technologies for early detection and next-generation sequencing in a regulated environment.
As a Senior/ Staff Research Associate supporting product and technology development, you will work with members within the team and interface with multiple teams including process engineering, clinical operations, research operations, and bioinformatics. You will be hands on in the lab and be required to design, implement, and validate new liquid biopsy sequencing assays for the early diagnosis and monitoring of all cancer types.
Duties and Responsibilities
- Develop, test and validate new NGS-based automated assays for oncology diagnostics
- Work in a team environment to identify areas for improvement in NGS assay work stream, propose and implement solutions
- Troubleshoot error modes in a clinical laboratory setting
- Synthesize large datasets and extract relevant trends using NGS data analysis tools (Python, R, IGV)
- Present data, proposals, and progress in various forums and to technical and non-technical audiences
- Train junior team members
- Ensure all work is performed and documented in compliance with applicable regulatory and quality practices (CLIA/CAP, IVD (Design Control), ISO13485)
Qualifications
Required skills
- Strong background in molecular biology and nucleic acid chemistry
- Solid foundation in laboratory techniques including sample preparation for NGS
- Proven track record of independent experimental planning, execution and data interpretation
- Analytical mindset to dissect complex problems, develop hypotheses, test them, synthesize results to inform solutions.
- Team player who enjoys working in a collaborative environment to accomplish large projects
- Demonstrated ability to document and communicate scientific data to an interdisciplinary audience
- Ability to adapt and be successful in a fast-paced environment
Preferred Skills
- Experience developing assays on automated liquid handling platforms
- Expertise in statistical analysis and visualization tools such as Python/R
- Experience developing products under design control
Education
BS or MS in biology, chemistry or related disciplines with a minimum of 5 years of industry experience or PhD. with a minimum of 1 year of industry experience.
Additional Information
Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.
Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
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